TSM5 — Tesamorelin 5mg
Synthetic analogue of growth hormone releasing hormone for metabolic and body composition research.
What is TSM5?
Tesamorelin is a synthetic analogue of endogenous Growth Hormone Releasing Hormone (GHRH), modified with a trans-3-hexenoic acid group at the N-terminus to improve stability and half-life. It is a 44-amino acid peptide that retains the full biological activity of native GHRH while offering enhanced resistance to enzymatic degradation.
Key Features
- Full-length GHRH analogue with enhanced stability
- Preserves physiological GH pulsatility
- Well-characterised receptor binding profile
- High purity ≥98% verified by mass spectrometry
Mechanism of Action
Tesamorelin binds to GHRH receptors on pituitary somatotrophs, stimulating the synthesis and pulsatile release of endogenous growth hormone. Unlike exogenous hGH administration, Tesamorelin preserves the natural pulsatile pattern of GH secretion and maintains feedback regulation. This makes it particularly valuable for studying physiological GH release mechanisms.
Research Applications
- GHRH receptor pharmacology and signalling
- Pulsatile GH secretion pattern studies
- Visceral adipose tissue biology research
- GH/IGF-1 axis modulation studies
- Metabolic syndrome pathway investigation
Reconstitution Guide
Reconstitute with sterile bacteriostatic water. Store at 2–8°C after reconstitution and use within 28 days.
Research Use Only. For research use only. Not for human or veterinary use. All products are intended solely for in vitro research and laboratory use. Helix Biotech does not endorse, encourage, or condone the use of any research compounds in humans or animals.
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